Svjetsko prvenstvo u motociklizmu u klasi 500cc za 1991. godinu je drugi put zaredom osvojio američki vozač Wayne Rainey na motociklu Yamaha YZR500 u momčadi Marlboro Team Roberts.
Raspored utrka i osvajači postolja 1991. godine je bilo na rasporedu 15 trkačih vikenda Svjetskog prvenstva i na svima su vožene utrke u klasi 500cc.
staza službeni naziv utrke motocikl pobjednik motocikl drugoplasirani motocikl trećeplasirani motocikl 1 ||<small> 24. ožujka 1991. || Suzuka ||VN Japana ||<small> Kibun Japanese Grand Prix Suzuka 1991 | Kevin Schwantz ||Suzuki || John Kocinski ||Yamaha | Kevin Schwantz Suzuki || Michael Doohan ||Honda || Wayne Rainey ||Yamaha | jumpingjack.nl, 1991 - GP, wayback arhiva racingmemo.free.fr, Les Championnats du Monde de Courses sur Route l'année 1991, pristupljeno 2. travnja 2024. racingmemo.free.fr, CHAMPIONNAT DU MONDE DE VITESSE MOTO - CLASSEMENTS COMPLETS - 1991 - 500cc, pristupljeno 2. travnja 2024. pilotegpmoto.com, GP 1991, preuzeto 2. travnja 2024. motorrad-autogrammkarten.de, Grand Prix Motorrad Weltmeisterschaft Podium / 1991, wayback arhiva motogp.com, Results / 1991 / JAPANESE GRAND PRIX 1991 / 500cc / RAC, pristupljeno 2. travnja 2024. motorsportstats.com, MotoGP / 1991 / JPN / Race, pristupljeno 2. travnja 2024. motorsportmagazine.com, 1991 Japanese MotoGP, pristupljeno 2. travnja 2024. autosport.com, MotoGP / 1991 / Japan, wayback arhiva europark.com, 1991 FIM WORLD CHAMPIONSHIP / ROAD RACE SERIES round 1 / KIBUN Japanese Grand Prix, pristupljeno 2. travnja 2024. |- |2 <small> 7. travnja 1991. Eastern Creek VN Australije ||<small> 1991 Tooheys Australian Motorcycle Grand Prix Wayne Rainey Yamaha Wayne Rainey Yamaha Wayne Rainey ||Yamaha Michael Doohan Honda John Kocinski Yamaha motogp.com, Results / 1991 / AUSTRALIAN GRAND PRIX 1991 / 500cc / RAC , pristupljeno 2. travnja 2024. motorsportstats.com, MotoGP / 1991 / AUS / Race, pristupljeno 2. travnja 2024. motorsportmagazine.com, 1991 Australian MotoGP, pristupljeno 2. travnja 2024. autosport.com, MotoGP / 1991 / Australia, wayback arhiva 3 ||<small> 21. travnja 1991. || Laguna Seca ||VN SAD-a ||<small> 1991 United States International Grand Prix | Wayne Rainey ||Yamaha || Wayne Rainey ||Yamaha | Wayne Rainey Yamaha || Michael Doohan ||Honda || Kevin Schwantz ||Suzuki | motogp.com, Results / 1991 / UNITED STATES GRAND PRIX 1991 / 500cc / RAC , pristupljeno 3. travnja 2024. motorsportstats.com, MotoGP / 1991 / USA / Race, pristupljeno 3. travnja 2024. motorsportmagazine.com, 1991 United States MotoGP, pristupljeno 3. travnja 2024. autosport.com, MotoGP / 1991 / USA, wayback arhiva |- |4 <small> 12. svibnja 1991. Jerez VN Španjolske ||<small> XLI Gran Premio de España Wayne Rainey Yamaha Wayne Rainey Yamaha Michael Doohan ||Honda John Kocinski Yamaha Wayne Rainey Yamaha motogp.com, Results / 1991 / SPANISH GRAND PRIX 1991 / 500cc / RAC, pristupljeno 3. travnja 2024. motorsportstats.com, MotoGP / 1991 / ESP / Race, pristupljeno 3. travnja 2024. motorsportmagazine.com, 1991 Spanish MotoGP, pristupljeno 3. travnja 2024. autosport.com, MotoGP / 1991 / Spain, wayback arhiva 5 ||<small> 19. svibnja 1991. || Misano (Santamonica) ||VN Italije ||<small> Gran Premio d'Italia | Wayne Rainey ||Yamaha || Wayne Rainey ||Yamaha | Michael Doohan Honda || John Kocinski ||Yamaha || Eddie Lawson ||Cagiva | motogp.com, Results / 1991 / ITALIAN GRAND PRIX 1991 / 500cc / RAC, pristupljeno 5. travnja 2024. motorsportstats.com, MotoGP / 1991 / ITA / Race, pristupljeno 5. travnja 2024. motorsportmagazine.com, 1991 Italian MotoGP, pristupljeno 5. travnja 2024. autosport.com, MotoGP / 1991 / Italy, wayback arhiva archiviolastampa.it, La Stampa, izdano 20. svibnja 1991., str 14 (Sport), preuzeto 5. travnja 2024. |- |6 <small> 26. svibnja 1991. Hockenheimring VN Njemačke ||<small> Großer Preis von Deutschland für Motorräder Michael Doohan Honda Kevin Schwantz Suzuki Kevin Schwantz ||Suzuki Wayne Rainey Yamaha Michael Doohan Honda motorsportstats.com, MotoGP / 1991 / DEU / Race, pristupljeno 5. travnja 2024. motorsportmagazine.com, 1991 German MotoGP, pristupljeno 5. travnja 2024. autosport.com, MotoGP / 1991 / Germany, wayback arhiva 7 ||<small> 9. lipnja 1991. || Salzburgring ||VN Austrije ||<small> Großer Preis von Österreich | Michael Doohan ||Honda || Wayne Rainey ||Yamaha | Michael Doohan Honda || Wayne Rainey ||Yamaha || Kevin Schwantz ||Suzuki | motogp.com, Results / 1991 / AUSTRIAN GRAND PRIX 1991 / 500cc / RAC, pristupljeno 8. travnja 2024. motorsportstats.com, MotoGP / 1991 / AUT / Race, pristupljeno 8. travnja 2024. motorsportmagazine.com, 1991 Austrian MotoGP, pristupljeno 8. travnja 2024. autosport.com, MotoGP / 1991 / Austria, wayback arhiva archiviolastampa.it, La Stampa, izdano 12. lipnja 1991., str 12 (Sport), preuzeto 8. travnja 2024. |- |8 <small> 16. lipnaj 1990. Jarama VN Europe ||<small> Gran Premio de Europa 1991 G.P. Yugoslavia Kevin Schwantz Suzuki Wayne Rainey Yamaha Wayne Rainey ||Yamaha Michael Doohan Honda Wayne Gardner Honda motogp.com, Results / 1991 / EUROPEAN GRAND PRIX 1991 / 500cc / RAC, pristupljeno 8. travnja 2024. motorsportstats.com, MotoGP / 1991 / EUR / Race, pristupljeno 8. travnja 2024. motorsportmagazine.com, 1991 European MotoGP, pristupljeno 8. travnja 2024. industrydocuments.ucsf.edu, MARLBORO NEWS - GRAND PRIX OF EUROPE JARAMA - RACE DAY - 910616, preuzeto 8. travnja 2024. 9 ||<small> 29. lipnja 1991. || Assen ||VN Nizozemske ||<small> 61e Dutch TT - Grote Prijs van Nederland der KNMV | Kevin Schwantz ||Suzuki || Kevin Schwantz ||Suzuki | Kevin Schwantz Suzuki || Wayne Rainey ||Yamaha || Wayne Gardner ||Honda | motogp.com, Results / 1991 / DUTCH TT 1991 / 500cc / RAC, pristupljeno 9. travnja 2024. motorsportstats.com, MotoGP / 1991 / NED / Race, pristupljeno 9. travnja 2024. motorsportmagazine.com, 1991 Dutch TT MotoGP, pristupljeno 9. travnja 2024. |- |10 <small> 21. srpnja 1991. Paul Ricard (Le Castellet) VN Francuske ||<small> Grand Prix de France Wayne Rainey Yamaha Wayne Rainey Yamaha Wayne Rainey ||Yamaha Michael Doohan Honda Eddie Lawson Cagiva motogp.com, Results / 1991 / FRENCH GRAND PRIX 1991 / 500cc / RAC, pristupljeno 9. travnja 2024. motorsportstats.com, MotoGP / 1991 / FRA / Race, pristupljeno 9. travnja 2024. motorsportmagazine.com, 1991 French MotoGP, pristupljeno 9. travnja 2024. 11 ||<small> 4. kolovoza 1991. || Donnington Park ||VN Britanije ||<small> Shell British Motorcycle Grand Prix | Kevin Schwantz ||Suzuki || Kevin Schwantz ||Suzuki | Kevin Schwantz Suzuki || Wayne Rainey ||Yamaha || Michael Doohan ||Honda | motorsportstats.com, MotoGP / 1991 / GBR / Race, pristupljeno 10. travnja 2024. motorsportmagazine.com, 1991 British MotoGP, pristupljeno 10. travnja 2024. autosport.com, MotoGP / 1991 / Great Britain, wayback arhiva |- |12 <small> 18. kolovoza 1991. Mugello VN San Marina ||<small> Gran Premio di San Marino Kevin Schwantz Suzuki Kevin Schwantz Suzuki Wayne Rainey ||Yamaha Kevin Schwantz Suzuki Michael Doohan Honda motorsportstats.com, MotoGP / 1991 / SMR / Race, pristupljeno 10. travnja 2024. motorsportmagazine.com, 1991 San Marino MotoGP, pristupljeno 10. travnja 2024. autosport.com, MotoGP / 1991 / San Marino, wayback arhiva 13 ||<small> 25. kolovoza 1991. || Brno ||VN Čehoslovačke ||<small> Grand Prix Brno - ČSFR | Wayne Rainey ||Yamaha || Wayne Rainey ||Yamaha | Wayne Rainey Yamaha || Michael Doohan ||Honda || John Kocinski ||Yamaha | motorsportstats.com, MotoGP / 1991 / CZE / Race, pristupljeno 11. travnja 2024. motorsportmagazine.com, 1991 Czechoslovakian MotoGP, pristupljeno 11. travnja 2024. autosport.com, MotoGP / 1991 / Czechoslovakia, wayback arhiva |- |14 <small> 8. rujna 1991. Le Mans - Bugatti Vitesse du Mans ||<small> Grand Prix Vitesse Du Mans John Kocinski Yamaha Michael Doohan Honda Kevin Schwantz ||Suzuki Michael Doohan Honda Wayne Rainey Yamaha motogp.com, Results / 1991 / VITESSE DU MANS GRAND PRIX 1991 / 500cc / RAC, pristupljeno 11. travnja 2024. motorsportstats.com, MotoGP / 1991 / FRA / Race, pristupljeno 11. travnja 2024. motorsportmagazine.com, 1991 Le Mans MotoGP, pristupljeno 11. travnja 2024. autosport.com, MotoGP / 1991 / Le Mans, wayback arhiva 15 ||<small> 29. rujna 1991. || Shah Alam ||VN Malezije ||<small> Lucky Strike Malaysia Grand Prix | John Kocinski ||Yamaha || John Kocinski ||Yamaha | John Kocinski Yamaha || Wayne Gardner ||Honda || Michael Doohan ||Honda | motogp.com, Results / 1991 / MALAYSIAN GRAND PRIX 1991 / 500cc / RAC, pristupljeno 12. travnja 2024. motorsportstats.com, MotoGP / 1991 / MYS / Race, pristupljeno 12. travnja 2024. motorsportmagazine.com, 1991 Malaysian MotoGP, pristupljeno 12. travnja 2024. autosport.com, MotoGP / 1991 / Malaysia, wayback arhiva
VN Jugoslavije na stazi Grobnik – otkazana radi nestabilne političke situacije i početka rata u Jugoslaviji VN Europe – održana kao zamjena za VN Jugoslavije VN Nizozemske - također navedena kao Dutch TT VN Britanije - također navedena kao VN Velike Britanije VN Brazila - bila u kalendaru, ali otkazana Vitesse du Mans – održana kao zamjena za VN Brazila
Poredak za vozače Sustav bodovanja Bodove osvaja prvih 15 vozača u utrci. U ukupnim bodvima za poredak su brisana dva najlošija rezultata.
{| class="wikitable" style="font-size: 85%; text-align:center" |- !pozicija u utrci |bgcolor="gold"|1. 2. ||bgcolor="goldenrod"|3. 4. ||5. 6. ||7. 8. ||9. 10. ||11. 12. ||13. 14. ||15. bodovi 20 17 15 13 11 10 9 8 7 6 5 4 3 2 1
mj. vozač konstruktor momčad (tim) motocikl bodova u poretku (ukupno bodova) 1. || Wayne Rainey Yamaha ||<center> 1 <small> Marlboro Team Roberts ||<small> Yamaha YZR500 (OWD3) 233 ||align="right"| (240) 2. || Michael Doohan Honda ||<center> 3 <small> Rothmans Honda ||<small> Honda NSR500 224 ||align="right"| (239) 3. || Kevin Schwantz Suzuki ||<center> 34 <small> Team Lucky Strike Suzuki ||<small> Suzuki RGV Γ 500 204 || |- |4. || John Kocinski ||Yamaha ||<center> 19 ||<small> Marlboro Team Roberts ||<small> Yamaha YZR500 (OWD3) ||rowspan="2" align="right"| 161 || |- |5. || Wayne Gardner ||Honda ||<center> 5 ||<small> Rothmans Honda ||<small> Honda NSR500 ||align="right"| (167) |- |6. || Eddie Lawson ||Cagiva ||<center> 7 ||<small> Cagiva Corse |||<small> Cagiva GP500 C591 ||align="right"| 126 || |- |7. || Juan Garriga ||Yamaha ||<center> 6 ||<small> Ducados Yamaha ||<small> Yamaha YZR500 (OWD3) ||align="right"| 121 ||align="right"| (125) |- |8. || Didier de Radiguès ||Suzuki ||<center> 27 ||<small> Team Lucky Strike Suzuki ||<small> Suzuki RGV Γ 500 ||align="right"| 105 ||align="right"| (107) |- |9. || Doug Chandler ||Yamaha ||<center> 21 ||<small> Team Roberts Yamaha Castrol ||<small> Yamaha YZR500 (OWD3) ||align="right"| 85 || |- |10. || Jean-Philippe Ruggia ||Yamaha ||<center> 8 ||<small> Yamaha Sonauto Mobil 1 ||<small> Yamaha YZR500 (OWD3) ||align="right"| 78 || |- |11. || Adrien Morillas ||Yamaha ||<center> 20 ||<small> Yamaha Sonauto Mobil 1 ||<small> Yamaha YZR500 (OWD3) ||align="right"| 71 || |- |12. || Eddie Laycock ||Yamaha ||<center> 17 ||<small> Millar Racing ||<small> Yamaha YZR500 '90 ||align="right"| 57 || |- |13. || Alex Barros ||Cagiva ||<center> 12 ||<small> Cagiva Corse |||<small> Cagiva GP500 C591 ||align="right"| 46 || |- |14. || Sito Pons ||Honda ||<center> 10 ||<small> Campsa Honda ||<small> Honda NSR500 ||rowspan="2" align="right"| 40 || |- |15. || Cees Doorakkers ||Honda ||<center> 16 ||<small> HEK-Bauwmachines ||<small> Honda RS500 || |- |16. || Marco Papa ||Honda Cagiva ||<center> 11 / 18 ||<small>Moto Club Milano - Team Papa Cagiva Corse ||<small> Honda RS500 Cagiva GP500 C591 ||align="right"| 36 || |- |17. || Niall Mackenzie ||Yamaha ||<center> 4 ||<small> Castrol Yamaha - Team Roberts Yamaha Sonauto Mobil 1 ||<small> Yamaha YZR500 ||align="right"| 34 || |- |18. || Michael Rudroff ||Honda ||<center> 32 / 35 / 39 ||<small> R.S. Rallye Sport ||<small> Honda RS500 ||align="right"| 36 || |-