"Thnks fr th Mmrs", "Dance, Dance" i "This Ain’t a Scene, It’s an Arms Race" ("I Write Sins Not Tragedies" jako intro) Akon – "Shake Down", "We Takin Over", "I Wanna Love You", "Smack That", "Don’t Matter" i "Mama Africa" Zach Braff (prezenter) John Mayer – "Belief", "Vultures", "Gravity" i "Waiting on the World to Change" Kevin Bacon (prezenter) Melissa Etheridge – "Imagine That", "What Happens Tomorrow" i "I Need to Wake Up" (z fragmentem "I Believe in Al Gore") Al Gore (przemówienie) Randy Jackson (prezenter) Alicia Keys – "New York, New York"/"For the Love of Money"/"Living for the City", "Mercy Mercy Me", "That’s The Thing About Love" i "If I Ain’t Got You" Rachel Weisz (prezenterka) Jane Goodall (przemówienie) Dave Matthews Band – "One Sweet World", "Don’t Drink the Water", "Anyone Seen the Bridge?" i "Too Much" Abigail i Spencer Breslin (prezenterzy) Kelly Clarkson – "Walk Away", "How I Feel", "Never Again", "Sober" i "Since U Been Gone" Rosario Dawson (prezenterka) Kanye West – "Heard ’Em Say", "All Falls Down", "Gold Digger", "Stronger", "Diamonds from Sierra Leone", "Can’t Tell Me Nothing", "Jesus Walks" i "Touch the Sky" Robert F. Kennedy Jr.